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Exemestane

Exemestane

Alias: Aromasin;Exemestan;Exemestane

Product Category: Pharmaceutical raw materials and intermediates

Assay: 98%min

CAS Registry Number:107868-30-4

Molecular formula: C20H24O2

Molecular Weight:296.40

Appearance: White or Almost White Crystalline Powder

Grade:Pharmaceutical Grade

Certification:ISO9001,GMP,USP,BP

Manufacturer:Carnoss

Usage: Developed to help fight breast cancer, Aromasin is one of the most powerful estrogen suppressing compounds

Other drugs in same class:Anastrozole,Letrozole,Tamoxifen citrate,Exemestane

Packaging Details:1-2 kg / aluminum foil bag, 25kg/ drum, as required

Delivery Time:2-4 days after received your payments

Storage:Shading, confined preservation

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Exemestane

Alias: Aromasin;Exemestan;Exemestane

Product Category: Pharmaceutical raw materials and intermediates

Assay: 98%min

CAS Registry Number:107868-30-4

Molecular formula: C20H24O2

Molecular Weight:296.40

Appearance: White or Almost White Crystalline Powder

Grade:Pharmaceutical Grade

Certification:ISO9001,GMP,USP,BP

Manufacturer:Carnoss

Usage: Developed to help fight breast cancer, Aromasin is one of the most powerful estrogen suppressing compounds

Other drugs in same class:Anastrozole,Letrozole,Tamoxifen citrate,Exemestane

Packaging Details:1-2 kg / aluminum foil bag, 25kg/ drum, as required

Delivery Time:2-4 days after received your payments

Storage:Shading, confined preservation

Muscle Building Sterioids Aromasin Anabolic Steroid Powder CAS NO.107868-30-4 Exemestane Anti-Estrogen
Quick Details:
Exemestane
Alias: Aromasin;Exemestan;Exemestane
Product Category: Pharmaceutical raw materials and intermediates
Assay: 98%min
CAS Registry Number:107868-30-4
Molecular formula: C20H24O2
Molecular Weight:296.40

Appearance: White or Almost White Crystalline Powder
Grade:Pharmaceutical Grade
Certification:ISO9001,GMP,USP,BP
Manufacturer:Carnoss
Usage: Developed to help fight breast cancer, Aromasin is one of the most powerful estrogen suppressing compounds
Other drugs in same class:Anastrozole,Letrozole,Tamoxifen citrate,Exemestane
Packaging Details:1-2 kg / aluminum foil bag, 25kg/ drum, as required
Delivery Time:2-4 days after received your payments
Storage:Shading, confined preservation

Product Description:
TEST ITEMS SPECIFICATION RESULTS
Description : White Crystalline Powder White Powder
Identification : Positive Positive
Specific Rotation : +288°~ +298° +290.2°
Assay(by HPLC) : 98.0~102.0% 98.64%
Absorbance(E1cm) : 465~495 482.5
Heavy Metals : 20PPm max <10PPm
Residue On Ignition : 0.1%max 0.03%
Related Substances : Total:1.5%max <1.3%
Single:0.5%max <0.4%
Loss On Drying : 0.5%max 0.19%
Residue Solvents : 0.2%max 0.10%
Melting Point : 191~195°C 193.5~195.0°C
Conclusion The specification conform with enterprise standard. 
Application: 
Exemestane is an oral steroidal aromatase inhibitor that is used in ER-positive breast cancer in addition to surgery and/or radiation in post-menopausal women. The main source of estrogen is the ovaries in premenopausal women, while in post-menopausal women most of the body's estrogen is produced via the conversion of androgens into estrogen by the aromatase enzyme in the peripheral tissues (i.e. adipose tissue like that of the breast) and a number of sites in the brain. Estrogen is produced locally via the actions of the aromatase enzyme in these peripheral tissues where it acts locally. Any circulating estrogen in post-menopausal women as well as men is the result of estrogen escaping local metabolism and entering the circulatory system.
 
Exemestane is an irreversible, steroidal aromatase inactivator, structurally related to the natural substrate androstenedione. It acts as a false substrate for the aromatase enzyme, and is processed to an intermediate that binds irreversibly to the active site of the enzyme causing its inactivation, an effect also known as "suicide inhibition." By being structurally similar to enzyme targets, Exemestane permanently binds to the enzymes, preventing them from converting androgen into estrogen.
 
Exemestane is taken in tablet form once a day. Patients can experience side effects like nausea, anxiety, shortness of breath, abdominal pain, bone pain, and chest pain. Side effects vary widely between patients and patients should report the side effects they experience to their doctors, as some may be indicators of dangerous complications. Shortness of breath and chest pain in particular are causes for concern in patients taking exemestane.