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Avanafil

Quick Details

Product name:Avanafil

Molecular Formula:C23H26ClN7O3 

Molecular Weight:483.9506 

Assay: 99% min. 

CAS: 330784-47-9

Character: White to Off-White Cyrstalline Solid.

Usage: Used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor. 

MOQ:10g

Production Capacity:5000kg/month

Specification:ISO9001,USP,BP,GMP

Trade Mark:CQSP

Port:Shenzhen/Shanghai,China

Package: as your inquiry.

Categories: Active Pharmaceutical Ingredients; Cnbio; Erectile Dysfunction; Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals; API's.

Shipping: DHL, EMS, FedEx, UPS

Delivery time: Parcel can be sent out within 24hours after your payment, 4~7 days to arrive.

Payment: Western Union, Moneygram, T/T, Bitcoin

HS CODE: 3001909099

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Quick Details

Product name:Avanafil

Molecular Formula:C23H26ClN7O3 

Molecular Weight:483.9506 

Assay: 99% min. 

CAS: 330784-47-9

Character: White to Off-White Cyrstalline Solid.

Usage: Used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor. 

MOQ:10g

Production Capacity:5000kg/month

Specification:ISO9001,USP,BP,GMP

Trade Mark:CQSP

Port:Shenzhen/Shanghai,China

Package: as your inquiry.

Categories: Active Pharmaceutical Ingredients; Cnbio; Erectile Dysfunction; Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals; API's.

Shipping: DHL, EMS, FedEx, UPS

Delivery time: Parcel can be sent out within 24hours after your payment, 4~7 days to arrive.

Payment: Western Union, Moneygram, T/T, Bitcoin

HS CODE: 3001909099

Pharmaceutical Active Ingredients Pharmaceutical Raw Materials Avanafil CAS 330784-47-9
Quick Details
Product name:Avanafil
Molecular Formula:C23H26ClN7O3 
Molecular Weight:483.9506 
Assay: 99% min. 
CAS: 330784-47-9

Character: White to Off-White Cyrstalline Solid.
Usage: Used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor. 
MOQ:10g
Production Capacity:5000kg/month
Specification:ISO9001,USP,BP,GMP
Trade Mark:CQSP
Port:Shenzhen/Shanghai,China
Package: as your inquiry.
Categories: Active Pharmaceutical Ingredients; Cnbio; Erectile Dysfunction; Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals; API's.
Shipping: DHL, EMS, FedEx, UPS
Delivery time: Parcel can be sent out within 24hours after your payment, 4~7 days to arrive.
Payment: Western Union, Moneygram, T/T, Bitcoin
HS CODE: 3001909099
Description:
Avanafil is a potent, highly selective phosphodiesterase 5 inhibitor, in vitro experiments showed that the selectivity of phosphodiesterase 5 stronger than. The compound dear compliance weak against other phosphodiesterase, and effect of adenosine receptor decreased, suggesting that the cardiovascular effects of avanafil should be weaker than .
Pre clinical study showed that avanafil and organic nitrate drugs taken in combination to reduce its on blood pressure was significantly weaker than and nitrate drugs with clothes. Moreover, avanafil inhibition of phosphodiesterase 6 is very weak, the relevant visual disturbance suppression may the enzyme phosphodiesterase 5 inhibitor induced and other.
Applications: 
Avanafil is a PDE5 inhibitor approved for erectile dysfunction by FDA on April 27, 2012 and by EMA on June 21, 2013. Avanafil acts by inhibiting a specific phosphodiesterase type 5 enzyme which is found in various body tissues, but primarily in the corpus cavernosum penis, as well as the retina. Other similar drugs are , tadalafil and vardenafil. The advantage of avanafil is that it has very fast onset of action compared with other PDE5 inhibitors. It is absorbed quickly, reaching a maximum concentration in about 30-45 minutes. About two-thirds of the participants were able to engage in sexual activity within 15 minutes. 
Side Effects:
The common side effects are usually mild and last a few hours, and may include facial flushing, an upset stomach, and headaches. Less common side effects are blurred vision, or perceiving a bluish tint in one's vision, and sensitivity to light. 
Most side effects experienced from taking these drugs are temporary. Clinical studies have revealed that the frequency of these side effects decreases over time. However, a rare side effect, vision loss, has been reported with people who have used PDE5 inhibitors. This loss of vision could be permanent and thus any vision-related side effects require an immediate visit to a doctor or medical facility. There is no evidence as yet that PDE5 inhibitors are the direct cause of vision loss.