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Estradiol Cypionate

Quick Details: 

Product name:Estradiol Cypionate

Alias:Depofemin

Purity : 99%min

CAS Registry Number: 313-06-4

Einecs No: 206-237-8

Molecular formula: C26H36O3

Molecular weight:396.56

Grade : Pharmaceutical Grade

Storage: Shading, confined preservation

Usage : pharmaceutical material, etc 

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Quick Details: 

Product name:Estradiol Cypionate

Alias:Depofemin

Purity : 99%min

CAS Registry Number: 313-06-4

Einecs No: 206-237-8

Molecular formula: C26H36O3

Molecular weight:396.56

Grade : Pharmaceutical Grade

Storage: Shading, confined preservation

Usage : pharmaceutical material, etc 

Pharmaceutical Grade Sex Hormone Estradiol Cypionate 99%min CAS 313-06-4
Quick Details: 
Product name:Estradiol Cypionate
Alias:Depofemin; Oestradiol Cypionate
Purity : 99%min
CAS Registry Number: 313-06-4
Einecs No: 206-237-8
Molecular formula: C26H36O3
Molecular weight:396.56

Grade : Pharmaceutical Grade
Storage: Shading, confined preservation
Usage : pharmaceutical material, etc 
Description:
1.Estradiol is a sex hormone that is present in both males and females, and is the most important form of estrogen in humans. In women, it plays a key role in the development and functioning of the reproductive system, as well as in the growth of certain bones. It also governs the distribution of body fat in women and is the main hormone responsible for the fact that women are shorter than men, on average. Both the ovaries and the adrenal glands produce it. 
2.The menstrual cycle in women involves predictable variations in the levels of several hormones, with estradiol being one of them. It is involved in the ovulation process and prepares the inner lining of the uterus for implantation, should the egg be fertilized. Certain tests done on baboons and other primates have indicated that his hormone also plays a continual role in maintaining a pregnancy, helping it to last for the full gestation period.
3.As a sex hormone, it also triggers many of the developments of the reproductive system that begin in puberty. It is present throughout the reproductive years, and declines during and after menopause. This decline is precisely what causes many of the symptoms of menopause, such as hot flashes and night sweats, vaginal dryness, and the loss of bone mass that may lead to osteoporosis. 
Specifications :
Product name  Estradiol cypionate
Appearance    White crystalline powder
Characteristics  White or creamy white, crystalline powder    conform
Melting point    176-180 °C    178~ 179°C
Water    ≤3.5%    pass
Assay    97 .0~ 103.0%    99.3%
Loss on drying    ≤0.5%    0.1%
Related substances    total impurities ≤1.0%    Pass
any individual impurity    ≤0.5%    Pass
Residual solvents    ethanol ≤0.5%    Pass 
Applications:   
1.Depofemin is a long-effect estrogen. Compared with Estradiol Valerate, it has stronger and longer effects. It is used for the treatment of ovarian insufficiency, amenorrhea, menopausal syndrome,senile vaginitis, and prostatic cancer. The compound of Depofemin and Medroxyprogesterone 17-acetate is a one-month long-term contraceptive injection.
2.Estradiol cypionate (INN, USAN; DepoEstradiol, Depofemin, Estradep, many others), or estradiol cipionate, is a synthetic ester, specifically the 3cyclopentylpropanoyl ester, of the natural estrogen,estradiol. It was first introduced in 1952 by Upjohn in the United States,and has been in widespread use since. Estradiol cypionate is absorbed more slowly than estradiol itself, and for that reason, it can be administered less often.
3.Estradiol cypionate was found to have the longest duration of action with a duration of ~11 days, while estradiol benzoate and estradiol valerate were found to last for 4–5 days and 7–8 days, respectively.In the female, estradiol acts as a growth hormone for tissue of the reproductive organs, supporting the lining of the vagina, the cervical glands, the endometrium, and the lining of the fallopian tubes. It enhancesgrowth of the myometrium. Estradiol appears necessary to maintain oocytes in the ovary.